Friday, March 02, 2007

Propolis Components Found to Be Cytotoxic, Strong Antioxidants

New Findings in Cancer Cell Biology Described from National Taiwan University, Graduate Institute of Biochemistry and Molecular Biology
Obesity, Fitness & Wellness Week, 3/10/2007

2007 MAR 10 - (NewsRx.com) -- Research findings, "Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis," are discussed in a new report. "We recently demonstrated that two new prenylflavanones, propolin A and propolin B, isolated and characterized from Taiwanese propolis, induced cytotoxicity effect in human melanoma A2058 cells and shows a strong capability to scavenge free radicals. In this study, propolin A effectively induced a cytotoxic effect on five different cancer cell lines," scientists in Taipei, Taiwan report...

The researchers concluded: "All these results indicated that propolin A and propolin B may trigger apoptosis of A2058 cells through mitochondria-dependent pathways and also shown that propolin A and propolin B were strong antioxidants."

Chen and colleagues published their study in Cancer Letters (Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis. Cancer Letters, 2007;245(1-2):218-31).

For more information, contact C.N. Chen, Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Section 1, Jen-Ai Road, Taipei 100, Taiwan, ROC.

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